Description

Methyl 2-Bromo-4-(Trifluoromethyl)Thiazole-5-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the thiazole core and trifluoromethyl group impart significant biological activity. Pharmaceutical, agrochemical, and specialty chemical R&D teams need it to efficiently construct complex molecules for drug discovery and crop protection applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases, inflammation, and central nervous system disorders.
• Agrochemical Synthesis: Serves as a key building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the creation of specialty polymers and advanced materials with unique electronic or optical properties.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing molecular probes and enzyme inhibitors to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trials.

Basic Information

Product Name	Methyl 2-Bromo-4-(Trifluoromethyl)Thiazole-5-Carboxylate
CAS No.	79247-82-8
Molecular Formula	C6H3BrF3NO2S
Molecular Weight	289.06 g/mol
Synonyms	Methyl 2-bromo-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate; 2-Bromo-4-(trifluoromethyl)thiazole-5-carboxylic acid methyl ester; 5-Thiazolecarboxylic acid, 2-bromo-4-(trifluoromethyl)-, methyl ester; Methyl 2-bromo-4-trifluoromethylthiazole-5-carboxylate; 79247-82-8; Methyl 2-bromo-4-(trifluoromethyl)-5-thiazolecarboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Bromo-4-(Trifluoromethyl)Thiazole-5-Carboxylate adheres to stringent quality management systems to ensure batch-to-batch consistency and reliability for your critical synthesis workflows. All material is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods including HPLC, GC, NMR, and IR spectroscopy. We are committed to meeting the exacting standards required for pharmaceutical and agrochemical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.