Description

4,7,8-Isoquinolinetriol, 1,2,3,4-Tetrahydro-1,2-Dimethyl-, (1S-Cis)- (9Ci) is a high-purity, stereochemically defined isoquinoline derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its unique polyhydroxylated tetrahydroisoquinoline structure makes it a valuable chiral building block and a potential precursor for bioactive molecule development. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex molecules and the exploration of new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Organic Synthesis Building Block: Used in the construction of complex natural product analogs and heterocyclic compounds due to its functionalized isoquinoline core.
• Medicinal Chemistry Research: Employed as a scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Research: Potential use as a tool compound or inhibitor in enzymatic studies, given its structural similarity to certain alkaloids.
• Agrochemical Development: Investigated as a precursor for novel plant protection agents and growth regulators.
• Catalyst Ligand Synthesis: May be utilized in the development of chiral ligands for asymmetric catalysis.

Basic Information

Product Name	4,7,8-Isoquinolinetriol, 1,2,3,4-Tetrahydro-1,2-Dimethyl-, (1S-Cis)- (9Ci)
CAS No.	79201-27-7
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	(1S,2S)-1,2-Dimethyl-1,2,3,4-tetrahydro-4,7,8-isoquinolinetriol; (1S-cis)-1,2-Dimethyl-1,2,3,4-tetrahydro-4,7,8-isoquinolinetriol; 1,2,3,4-Tetrahydro-1,2-dimethyl-4,7,8-isoquinolinetriol, (1S-cis)-; 4,7,8-Isoquinolinetriol, 1,2,3,4-tetrahydro-1,2-dimethyl-, (1S-cis)-; 79201-27-7; cis-1,2-Dimethyl-1,2,3,4-tetrahydroisoquinoline-4,7,8-triol
EINECS	Contact for details

Quality Control

Our 4,7,8-Isoquinolinetriol, 1,2,3,4-Tetrahydro-1,2-Dimethyl-, (1S-Cis)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.