Description

4,6,7-Isoquinolinetriol, 1,2,3,4-Tetrahydro-1,2-Dimethyl-, (1R-Trans)- (9Ci) is a high-purity, stereochemically defined isoquinoline derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a sophisticated chiral building block and a key intermediate for the development of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for exploring new therapeutic agents targeting the central nervous system and other complex biological pathways.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, especially in neuroscience and oncology.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for synthesizing libraries of compounds for high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Tool Compound: Employed in academic and industrial laboratories to study enzyme mechanisms or receptor interactions due to its specific stereochemistry and functional groups.
• Advanced Organic Synthesis: Serves as a versatile starting material for the synthesis of complex natural product analogs and other fine chemicals requiring precise stereocontrol.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	4,6,7-Isoquinolinetriol, 1,2,3,4-Tetrahydro-1,2-Dimethyl-, (1R-Trans)- (9Ci)
CAS No.	79201-25-5
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	(1R,2S)-1,2-Dimethyl-1,2,3,4-tetrahydro-4,6,7-isoquinolinetriol; (1R-trans)-1,2-Dimethyl-1,2,3,4-tetrahydroisoquinoline-4,6,7-triol; 1,2,3,4-Tetrahydro-1,2-dimethyl-4,6,7-isoquinolinetriol, (1R-trans)-; Tetrahydroisoquinolinetriol derivative; Chiral tetrahydroisoquinoline triol
EINECS	Contact for details

Quality Control

Every batch of 4,6,7-Isoquinolinetriol, 1,2,3,4-Tetrahydro-1,2-Dimethyl-, (1R-Trans)- (9Ci) is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research-grade chemicals. Certificates of Analysis (COA) detailing purity, chiral purity, and identity are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.