Description

4,6,7-Isoquinolinetriol, 1,2,3,4-Tetrahydro-1,2-Dimethyl-, (1S-Cis)- (9Ci) is a high-purity, stereochemically defined isoquinoline derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and a key intermediate for developing novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of potential therapeutic agents targeting neurological and cardiovascular systems.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular applications.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies and the synthesis of complex alkaloid analogs.
• Biochemical Research: Employed in studies investigating enzyme inhibition or receptor binding due to its specific stereochemistry and functional groups.
• Organic Synthesis: Serves as a versatile building block for constructing more complex polycyclic or heterocyclic compounds in academic and industrial laboratories.
• Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Item	Detail
Product Name	4,6,7-Isoquinolinetriol, 1,2,3,4-Tetrahydro-1,2-Dimethyl-, (1S-Cis)- (9Ci)
CAS No.	79201-23-3
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	(1S,2S)-1,2-Dimethyl-1,2,3,4-tetrahydro-4,6,7-isoquinolinetriol; (1S-cis)-1,2-Dimethyl-1,2,3,4-tetrahydro-4,6,7-isoquinolinetriol; 1,2,3,4-Tetrahydro-1,2-dimethyl-4,6,7-isoquinolinetriol, (1S-cis)-; NSC 339579; Tetrahydroisoquinolinetriol derivative
EINECS	Contact for details

Quality Control

Our 4,6,7-Isoquinolinetriol, 1,2,3,4-Tetrahydro-1,2-Dimethyl-, (1S-Cis)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.