Description

1-[3-(Trifluoromethyl)Benzyl]-1H-Indole-2,3-Dione is a specialized organic compound belonging to the isatin derivative class, characterized by a trifluoromethylbenzyl substituent. This molecular architecture makes it a valuable high-purity building block and key intermediate in advanced synthetic chemistry. It is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for developing novel active ingredients, where its unique fluorinated structure imparts desirable properties to target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Organic Light-Emitting Diode (OLED) Materials: Acts as an electron-transport or host material precursor in the manufacture of high-performance display and lighting technologies.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalytic processes.
• Fluorescent Probe and Dye Synthesis: Utilized as a core structure for developing sensitive chemical sensors and imaging agents.
• Academic and Industrial R&D: A versatile scaffold for medicinal chemistry and material science research in university and corporate laboratories.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Benzyl]-1H-Indole-2,3-Dione
CAS No.	79183-40-7
Molecular Formula	C16H10F3NO2
Molecular Weight	305.25 g/mol
Synonyms	3-[(3-Trifluoromethyl)benzyl]isatin; 1-[(3-Trifluoromethyl)phenyl]methyl]-1H-indole-2,3-dione; 1-(3-Trifluoromethylbenzyl)indoline-2,3-dione; 1-(α,α,α-Trifluoro-m-tolyl)isatin; Isatin, 1-[(3-(trifluoromethyl)phenyl)methyl]-; 79183-40-7; m-Trifluoromethylbenzylisatin
EINECS	Contact for details

Quality Control

Our 1-[3-(Trifluoromethyl)Benzyl]-1H-Indole-2,3-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.