Description

Dl-Valine-3-D1 is a deuterium-labeled isotopologue of the amino acid DL-valine, specifically deuterated at the 3-position. This stable isotope-labeled compound is a critical tool for advanced analytical and research applications, providing a non-radioactive tracer with distinct mass spectral properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for applications such as metabolic studies, internal standards for mass spectrometry, and mechanistic research.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a crucial quantitative internal standard in LC-MS and GC-MS analyses for valine and related compounds, improving accuracy and precision.
• Metabolic Pathway Tracing: Used in pharmacokinetic, pharmacodynamic, and metabolic flux studies to track the absorption, distribution, metabolism, and excretion (ADME) of valine-containing molecules.
• Mechanistic Biochemical Research: Aids in elucidating reaction mechanisms and enzymatic processes involving valine through isotope effect studies.
• Pharmaceutical Development: Employed in the synthesis and testing of deuterated drug candidates, where deuterium incorporation can alter metabolic profiles.
• Proteomics and Amino Acid Analysis: Facilitates accurate quantification of valine in complex biological samples like proteins, peptides, and physiological fluids.
• Quality Control & Method Validation: Acts as a reference material in analytical method development and validation within quality control laboratories.

Basic Information

Product Name	Dl-Valine-3-D1
CAS No.	79168-24-4
Molecular Formula	C5H10DNO2
Molecular Weight	118.16 g/mol (approx.)
Synonyms	(±)-2-Amino-3-(methyl-d)butanoic acid; DL-Valine-3-d; DL-Valine-(3-d); 2-Azaniumyl-3-(methyl-d)butanoate; Valine-d1 (3-d); Racemic Valine-3-D1; 3-Deutero-DL-valine; (RS)-Valine-3-D1
EINECS	Contact for details

Quality Control

Our Dl-Valine-3-D1 is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high chemical purity, isotopic enrichment, and batch-to-batch consistency. We provide detailed Certificates of Analysis (COA) that include specifications for isotopic purity (D-enrichment), chemical purity (by HPLC), and identification (by IR and NMR). Our quality systems support compliance with relevant standards for research and analytical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.