Description

3-(Piperidin-4-Yl)Indolin-2-One Hydrochloride is a high-purity pharmaceutical intermediate and research chemical. This compound is a key building block in medicinal chemistry, particularly valued for its indolinone-piperidine scaffold which is prevalent in bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including kinase inhibitors and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Kinase Inhibitor Research: Serves as a core scaffold for the development of novel kinase inhibitors for oncology and inflammatory diseases.
• CNS Drug Discovery: Used in research programs focused on neurological disorders due to the pharmacophore's relevance to CNS targets.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular signaling.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and cGMP manufacturing of clinical trial materials.
• Academic & Contract Research: Utilized in universities and CROs for exploratory synthetic chemistry and hit-to-lead optimization.

Basic Information

Product Name	3-(Piperidin-4-Yl)Indolin-2-One Hydrochloride
CAS No.	79098-85-4
Molecular Formula	C13H16N2O·HCl
Molecular Weight	252.74 g/mol
Synonyms	3-(4-Piperidinyl)-2-indolinone hydrochloride; 2-Oxo-3-(4-piperidinyl)indoline hydrochloride; 3-(Piperidin-4-yl)indolin-2-one HCl; 2-Indolinone, 3-(4-piperidinyl)-, hydrochloride; 79098-85-4; UNII-9F8H9J8F0M; 9F8H9J8F0M
EINECS	Contact for details

Quality Control

Our 3-(Piperidin-4-Yl)Indolin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.