Description

1-Oxo-4-Phenyl-1,2-Dihydroisoquinoline-3-Carboxylic Acid is a high-value heterocyclic carboxylic acid derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique fused isoquinoline core structure makes it a versatile building block for constructing complex molecules with potential biological activity. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) in high-throughput screening libraries.
• Organic Synthesis Building Block: Employed in the construction of complex polycyclic frameworks due to its reactive carboxylic acid and ketone functionalities.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection products.
• Academic & R&D Laboratories: Utilized in fundamental research exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	1-Oxo-4-Phenyl-1,2-Dihydroisoquinoline-3-Carboxylic Acid
CAS No.	78945-99-0
Molecular Formula	C₁₆H₁₁NO₃
Molecular Weight	265.26 g/mol
Synonyms	4-Phenyl-1,2-dihydro-1-oxoisoquinoline-3-carboxylic acid; 4-Phenyl-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid; 3-Carboxy-4-phenyl-1,2-dihydro-1-oxoisoquinoline; 1,2-Dihydro-1-oxo-4-phenylisoquinoline-3-carboxylic acid; 4-Phenyl-1-oxo-1,2-dihydro-3-isoquinolinecarboxylic acid; 1-Oxo-4-phenyl-1,2-dihydro-3-isoquinolinecarboxylic acid; 3-Isoquinolinecarboxylic acid, 1,2-dihydro-1-oxo-4-phenyl-
EINECS	Contact for details

Quality Control

Our 1-Oxo-4-Phenyl-1,2-Dihydroisoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.