Description

1H-Indole-3-Carbonyl Chloride, 4,7-Dihydroxy- (9Ci) is a specialized, high-purity chemical building block featuring a reactive acid chloride group on the indole scaffold. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting serotonin-related pathways or with indole-based structures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that incorporate functionalized indole motifs.
• Bioconjugation & Probe Synthesis: The reactive carbonyl chloride group enables coupling with amines or alcohols to create fluorescent probes, affinity labels, or protein conjugates for biochemical research.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialized polymers and advanced organic materials.
• Academic & Contract Research: Essential for synthetic organic chemistry research in universities and CROs (Contract Research Organizations) exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	1H-Indole-3-Carbonyl Chloride, 4,7-Dihydroxy- (9Ci)
CAS No.	78942-72-0
Molecular Formula	C9H6ClNO3
Molecular Weight	211.60 g/mol
Synonyms	4,7-Dihydroxy-1H-indole-3-carbonyl chloride; 4,7-Dihydroxyindole-3-carbonyl chloride; 1H-Indole-3-carbonyl chloride, 4,7-dihydroxy-; 4,7-Dihydroxy-1H-indole-3-carboxylic acid chloride; 4,7-Dihydroxyindole-3-carboxylic acid chloride; 78942-72-0; 4,7-Dihydroxyindole-3-Carboxylic Acid Chloride
EINECS	Contact for details

Quality Control

Every batch of 1H-Indole-3-Carbonyl Chloride, 4,7-Dihydroxy- (9Ci) is produced and tested under strict quality management protocols to ensure consistency and reliability for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting standards for purity and identity. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 1.0%
Solubility	Soluble in strong acid/organic solvent

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.