Description

1-[(Thiophen-3-Yl)Carbonyl]Pyrrolidine is a high-purity organic building block featuring a thiophene-pyrrolidine scaffold, a structure of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the thiophene moiety can contribute to biological activity.
• Material Science Research: Serves as a precursor for organic electronic materials, such as conductive polymers and organic semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP conditions.
• Academic & Industrial R&D: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	1-[(Thiophen-3-Yl)Carbonyl]Pyrrolidine
CAS No.	78909-14-5
Molecular Formula	C9H11NOS
Molecular Weight	181.26 g/mol
Synonyms	1-(Thiophene-3-carbonyl)pyrrolidine; 1-(Thiophen-3-ylcarbonyl)pyrrolidine; 3-Pyrrolidin-1-ylcarbonylthiophene; 1-(3-Thienylcarbonyl)pyrrolidine; N-(Thiophen-3-ylcarbonyl)pyrrolidine; Pyrrolidine, 1-(3-thienylcarbonyl)-; 3-(Pyrrolidine-1-carbonyl)thiophene
EINECS	Contact for details

Quality Control

Our 1-[(Thiophen-3-Yl)Carbonyl]Pyrrolidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is supplied with every shipment. For advanced applications, we can tailor quality protocols to meet specific research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.