Description

3-(tert-Butylamino)Acetylindole Hydrochloride Hydrate is a high-purity indole derivative and a key pharmaceutical intermediate. This compound matters for its role in the synthesis of complex molecules, offering a critical building block for research and development. It is primarily needed by pharmaceutical manufacturers, biotechnology research organizations, and advanced organic synthesis laboratories developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and neurological disorder research.
• Biochemical Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of receptor-targeted compounds.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic frameworks and indole-based molecular libraries.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for advanced organic chemistry and drug discovery projects.

Basic Information

Product Name	3-(tert-Butylamino)Acetylindole Hydrochloride Hydrate
CAS No.	78907-16-1
Molecular Formula	C14H19N2O•HCl•xH2O
Molecular Weight	266.77 (anhydrous freebase)
Synonyms	1H-Indole-3-acetamide, N-(1,1-dimethylethyl)-2-oxo-, hydrochloride, hydrate; 3-[(2-Oxo-2-[(1,1-dimethylethyl)amino]ethyl]-1H-indole hydrochloride hydrate; 3-(N-tert-Butylacetamido)indole hydrochloride hydrate; 3-(tert-Butylcarbamoylmethyl)indole hydrochloride hydrate; tert-Butyl-(3-indolylacetyl)amine hydrochloride hydrate; N-tert-Butyl-2-(1H-indol-3-yl)acetamide hydrochloride hydrate
EINECS	Contact for details

Quality Control

Our 3-(tert-Butylamino)Acetylindole Hydrochloride Hydrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed HPLC, NMR, and LC-MS data are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.