Description

1-Chloro-6-(5-Ethynylthiophen-2-Yl)Hexa-3,5-Diyn-2-Ol CAS NO 78876-53-6 is a specialized organic intermediate featuring a unique conjugated diyne and thiophene-based molecular architecture. This compound is valued for its role as a key building block in advanced materials science and pharmaceutical research, where its reactive functional groups enable precise molecular construction. It is primarily sought by R&D chemists and process development scientists in the fields of organic electronics, polymer chemistry, and medicinal chemistry for synthesizing novel functional molecules.

Application

• Organic Semiconductor Precursor: Serves as a critical monomer for the synthesis of conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and photovoltaic cells.
• Pharmaceutical Intermediate: Used in the research and development of new active pharmaceutical ingredients (APIs), particularly those targeting specific biological pathways where the thiophene and alkyne motifs are pharmacologically relevant.
• Ligand Synthesis for Catalysis: Acts as a starting material for creating sophisticated ligands used in transition metal catalysis, enhancing reaction selectivity and efficiency.
• Material Science Research: Employed in developing novel organic frameworks, sensors, and non-linear optical (NLO) materials due to its extended π-conjugation system.
• Click Chemistry Substrate: The terminal alkyne group makes it an ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, a cornerstone of bioconjugation and polymer functionalization.
• Agrochemical Intermediate: Potential use in the synthesis of next-generation crop protection agents with novel modes of action.

Basic Information

Item	Details
Product Name	1-Chloro-6-(5-Ethynylthiophen-2-Yl)Hexa-3,5-Diyn-2-Ol
CAS No.	78876-53-6
Molecular Formula	C12H7ClOS
Molecular Weight	234.70 g/mol
Synonyms	1-Chloro-6-(5-ethynyl-2-thienyl)-3,5-hexadiyn-2-ol; 2-Thiopheneethanol, 5-ethynyl-β-[3-chloro-2-propyn-1-yl]-; 78876-53-6; 5-Ethynyl-2-thiophenehexadiynol chloride derivative; Chloro(ethynylthienyl)hexadiynol; Thiophene alkyne diol chloride; Conjugated thiophene-diyne intermediate
EINECS	Contact for details

Quality Control

Every batch of 1-Chloro-6-(5-Ethynylthiophen-2-Yl)Hexa-3,5-Diyn-2-Ol is synthesized and purified under controlled conditions to ensure high chemical purity and lot-to-lot consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area, away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.