Description

5,8,11,14-Eicosatetraenyl (3-Aminopropyl)Phosphonate is a specialized synthetic phospholipid derivative, a key intermediate in the synthesis of complex bioactive molecules. Its unique structure, featuring a polyunsaturated eicosatetraenyl chain and an aminopropyl phosphonate group, makes it a valuable building block for advanced lipid research and pharmaceutical development. This compound is primarily utilized by researchers and manufacturers in the life sciences sector for creating novel lipid-based drug delivery systems, targeted therapeutics, and as a precursor for labeled phospholipids used in diagnostic assays.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel phospholipid-based active pharmaceutical ingredients (APIs) and prodrugs.
• Lipid Nanoparticle (LNP) Research: Used in the development and formulation of next-generation lipid nanoparticles for mRNA and gene therapy delivery systems.
• Bioconjugation & Probe Synthesis: Serves as a backbone for creating fluorescent or radioactive probes for cell membrane studies and diagnostic imaging.
• Biomimetic Membrane Studies: Incorporated into liposomes and artificial membranes to study membrane fluidity, protein-lipid interactions, and signaling pathways.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies aimed at discovering new anti-inflammatory or anti-cancer agents.
• High-Purity Reference Standard: Supplied as a certified reference material for analytical method development and quality control in pharmaceutical laboratories.

Basic Information

Product Name	5,8,11,14-Eicosatetraenyl (3-Aminopropyl)Phosphonate
CAS No.	78859-47-9
Molecular Formula	C₂₃H₄₂NO₃P
Molecular Weight	411.56 g/mol
Synonyms	(3-Aminopropyl) 5,8,11,14-Eicosatetraenylphosphonate; 5,8,11,14-Eicosatetraenoic Acid (3-Aminopropyl) Phosphonate; Arachidonyl (3-Aminopropyl)Phosphonate; 1-Amino-3-(5,8,11,14-eicosatetraenyloxy)propan-2-ylphosphonic Acid; ETE-APP; Arachidonylamino Propyl Phosphonate; Phosphonolipid Intermediate A6
EINECS	Contact for details

Quality Control

Every batch of 5,8,11,14-Eicosatetraenyl (3-Aminopropyl)Phosphonate is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your research or cGMP requirements. A detailed Certificate of Analysis (COA), including results for purity (HPLC), identity (NMR, IR), and specific impurity profiles, is supplied with each shipment to guarantee reliable and reproducible performance in your applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at -20°C or below to minimize oxidation and hydrolysis. The material is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.