Description

2-Naphthol-D8 is a deuterium-labeled isotopologue of 2-naphthol, a key aromatic compound. This high-purity labeled standard is essential for ensuring accuracy and reliability in quantitative analytical methods, particularly mass spectrometry. It is primarily used by researchers and quality control laboratories in the pharmaceutical, environmental, and chemical synthesis sectors for use as an internal standard, tracer, or reagent in deuterium-labeling studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used for the precise quantification of 2-naphthol and related compounds in complex matrices.
• Metabolic Pathway Tracing: Serves as a stable isotopic tracer in pharmacokinetic and drug metabolism studies.
• Deuterated Reagent/Synthon: Employed in organic synthesis to introduce deuterium labels into target molecules for mechanistic studies or to alter physical properties.
• Environmental Analysis: Aids in the detection and quantification of naphthalene derivatives and polycyclic aromatic hydrocarbon (PAH) metabolites in environmental samples.
• NMR Spectroscopy: Useful as a solvent or reference compound in deuterated solvent systems or for specific spectroscopic investigations.
• Quality Control & Method Development: Critical for developing and validating sensitive analytical methods in regulatory and R&D environments.

Basic Information

Product Name	2-Naphthol-D8
CAS No.	78832-61-8
Molecular Formula	C10D8O
Molecular Weight	160.24 g/mol
Synonyms	2-Naphthalenol-D8; β-Naphthol-D8; 2-Hydroxynaphthalene-D8; Isonaphthol-D8; Deuteronaphthol; [D8]-2-Naphthol; Perdeuterated 2-naphthol; 2-Naphthol (ring-D8)
EINECS	Contact for details

Quality Control

Our 2-Naphthol-D8 is produced under strict quality protocols to ensure high isotopic purity and chemical integrity, suitable for demanding analytical applications. Each batch is characterized by NMR and MS to confirm deuteration level and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (typically >98% D), chemical purity (by HPLC), and other relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (Deuteration)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.