Description

D(-)-Ac-α-Phenylglycinol is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. Its value lies in its role as a versatile precursor for the asymmetric synthesis of a wide range of bioactive molecules, including active pharmaceutical ingredients (APIs). This compound is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for chiral synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in the development of protease inhibitors, β-lactam antibiotics, and other therapeutics.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for transition metal catalysts, enabling highly enantioselective transformations in organic synthesis.
• Agrochemical Synthesis: Serves as a building block for the production of chiral pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require precise stereochemical control.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research within university and industrial laboratories.

Basic Information

Product Name	D(-)-Ac-α-Phenylglycinol
CAS No.	78761-26-9
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(R)-2-Acetamido-2-phenylethanol; (R)-N-Acetyl-2-amino-2-phenylethanol; D-(-)-N-Acetyl-α-phenylglycinol; (R)-N-Acetyl-2-phenylglycinol; (R)-2-(Acetylamino)-2-phenylethanol; Ac-D-Phg-ol; (R)-Ac-Phenylglycinol; D-N-Acetylphenylglycinol
EINECS	Contact for details

Quality Control

Our D(-)-Ac-α-Phenylglycinol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes critical parameters such as chiral purity (enantiomeric excess), chemical purity (HPLC), and identification data. We are committed to meeting the stringent requirements of pharmaceutical and advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.