Description

Ethyl 2-(2-[3-(Trifluoromethyl)Phenyl]-1,3-Thiazol-4-Yl)Acetate is a high-value fluorinated heterocyclic building block, specifically an ester-functionalized thiazole derivative. This compound is engineered to provide a versatile and reactive scaffold for advanced organic synthesis, offering a strategic entry point for introducing complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting a range of therapeutic areas, leveraging the bioisosteric properties of the trifluoromethylphenyl-thiazole core.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the fluorine atoms and heterocyclic structure can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed as a versatile building block in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies.
• Ligand & Catalyst Development: The thiazole nitrogen can act as a coordinating site, making it useful in designing novel ligands for catalytic systems.

Basic Information

Product Name	Ethyl 2-(2-[3-(Trifluoromethyl)Phenyl]-1,3-Thiazol-4-Yl)Acetate
CAS No.	78743-00-7
Molecular Formula	C₁₄H₁₂F₃NO₂S
Molecular Weight	315.31 g/mol
Synonyms	Ethyl 2-[2-[3-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl]acetate; 4-Thiazoleacetic acid, 2-[3-(trifluoromethyl)phenyl]-, ethyl ester; Ethyl (2-(3-(trifluoromethyl)phenyl)thiazol-4-yl)acetate; 2-(2-(3-(Trifluoromethyl)phenyl)thiazol-4-yl)acetic acid ethyl ester; Acetic acid, 2-[2-[3-(trifluoromethyl)phenyl]-4-thiazolyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-(2-[3-(Trifluoromethyl)Phenyl]-1,3-Thiazol-4-Yl)Acetate adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.