Description

trans-2-Bromo-1-Indanol is a versatile chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its unique bromohydrin structure on an indane scaffold makes it a valuable precursor for constructing complex molecules with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel chiral ligands.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of potential drug candidates, especially in central nervous system (CNS) and cardiovascular research.
• Asymmetric Catalysis: Used in the preparation of chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Synthesis: Intermediate in the development of novel, stereochemically defined pesticides and herbicides.
• Material Science Research: Building block for creating functionalized organic molecules with potential applications in advanced materials.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, particularly in ring-opening and substitution reactions.

Basic Information

Product Name	trans-2-Bromo-1-Indanol
CAS No.	78684-69-2
Molecular Formula	C9H9BrO
Molecular Weight	213.07 g/mol
Synonyms	(1R,2S)-2-Bromo-2,3-dihydro-1H-inden-1-ol; (1S,2R)-2-Bromo-2,3-dihydro-1H-inden-1-ol; trans-2-Bromoindan-1-ol; 2-Bromo-1-indanol (trans-); 2,3-Dihydro-2-bromo-1H-inden-1-ol; (±)-trans-2-Bromo-1-indanol; rac-trans-2-Bromoindan-1-ol
EINECS	Contact for details

Quality Control

Our trans-2-Bromo-1-Indanol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. Due to its light-sensitive nature, handling and packaging are performed under controlled lighting conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% de (trans-isomer)
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.