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(4-Amino-2-Methylthiophen-3-Yl)Methyl Hydrogen Carbonate Hydrochloride CAS NO 78648-43-8


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CAS No.:78648-43-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(4-Amino-2-Methylthiophen-3-Yl)Methyl Hydrogen Carbonate Hydrochloride is a specialized organic salt compound that serves as a critical building block in advanced chemical synthesis. Its value lies in its unique molecular structure, which incorporates both a protected amino-thiophene moiety and a carbonate ester, making it a versatile intermediate for constructing complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals where precise molecular architecture is required.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
  • Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides, leveraging its thiophene-based heterocyclic core.
  • Fine Chemical Production: Serves as a high-value building block for creating complex molecules in custom synthesis and contract manufacturing.
  • Organic Synthesis Research: A valuable reagent in academic and industrial R&D labs for methodology development and exploring new chemical spaces.
  • Material Science Precursor: Potential intermediate in the synthesis of organic semiconductors and specialty polymers.

Basic Information

Product Name (4-Amino-2-Methylthiophen-3-Yl)Methyl Hydrogen Carbonate Hydrochloride
CAS No. 78648-43-8
Molecular Formula C8H12ClNO3S
Molecular Weight 237.70 g/mol
Synonyms Carbonic acid, [(4-amino-2-methyl-3-thienyl)methyl] ester, hydrochloride; 3-Thiophenemethanol, 4-amino-2-methyl-, hydrogen carbonate (ester), hydrochloride; (4-Amino-2-methyl-3-thienyl)methyl hydrogen carbonate hydrochloride; 4-Amino-2-methylthiophene-3-methyl hydrogen carbonate hydrochloride
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Quality Control

Our production of (4-Amino-2-Methylthiophen-3-Yl)Methyl Hydrogen Carbonate Hydrochloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results. We operate under a cGMP-compliant quality management system to meet the exacting standards of pharmaceutical and advanced chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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