Description

14-Methoxy-17-(cyclopropylmethyl)-3-methylmorphinan-6-one is a high-purity synthetic morphinan derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analytical characterization of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories, analytical testing facilities, and fine chemical manufacturers engaged in the development of central nervous system (CNS) active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel opioid receptor modulators and other CNS-targeting active pharmaceutical ingredients (APIs).
• Reference Standard: Used in analytical chemistry for method development, validation, and quality control (QC) testing of related drug substances and finished products.
• Biochemical Research: Employed in pharmacological studies to investigate receptor binding affinity, metabolic pathways, and structure-activity relationships (SAR).
• Process Development: Serves as a starting material or intermediate in scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Impurity Profiling: Utilized as a certified reference material to identify and quantify related substances and degradation products in API batches.

Basic Information

Product Name	14-Methoxy-17-(Cyclopropylmethyl)-3-Methylmorphinan-6-One
CAS No.	78506-32-8
Molecular Formula	C23H31NO2
Molecular Weight	353.50 g/mol
Synonyms	14-Methoxy-17-(cyclopropylmethyl)-3-methylmorphinan-6-one; 6-Oxo-14-methoxy-17-(cyclopropylmethyl)-3-methylmorphinan; 17-Cyclopropylmethyl-14-methoxy-3-methyl-6-oxomorphinan; 14-Methoxy-17-cyclopropylmethyl-3-methyl-6-oxomorphinan; 14-Methoxy-3-methyl-17-(cyclopropylmethyl)morphinan-6-one; 6-Keto-14-methoxy-17-cyclopropylmethyl-3-methylmorphinan; 17-Cyclopropylmethyl-14-methoxy-3-methylmorphinan-6-one
EINECS	Contact for details

Quality Control

Our 14-Methoxy-17-(cyclopropylmethyl)-3-methylmorphinan-6-one is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.