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1-(4-Chlorobenzoyl)-3-(2-(1H-Imidazol-1-Yl)-2-Oxoethyl)-5-Methoxy-2-Methyl-1H-Indole CAS NO 78486-46-1


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CAS No.:78486-46-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(4-Chlorobenzoyl)-3-(2-(1H-Imidazol-1-Yl)-2-Oxoethyl)-5-Methoxy-2-Methyl-1H-Indole is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate with significant pharmacological research value. This compound is a key synthetic precursor in the development of advanced analgesic and anti-inflammatory agents, offering a critical building block for pharmaceutical R&D. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the synthesis of novel therapeutic compounds.

Application

  • Pharmaceutical Intermediate: A crucial building block in the synthesis of novel non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
  • Biochemical Research: Used in pharmacological studies to investigate anti-inflammatory pathways and develop new drug candidates.
  • Fine Chemical Synthesis: Serves as a specialized intermediate for creating complex organic molecules in medicinal chemistry.
  • Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
  • Academic Research: Utilized in university and institutional labs for studying organic synthesis methodologies and structure-activity relationships (SAR).

Basic Information

Product Name 1-(4-Chlorobenzoyl)-3-(2-(1H-Imidazol-1-Yl)-2-Oxoethyl)-5-Methoxy-2-Methyl-1H-Indole
CAS No. 78486-46-1
Molecular Formula C22H18ClN3O3
Molecular Weight 407.85 g/mol
Synonyms 1-(4-Chlorobenzoyl)-3-(2-(1H-imidazol-1-yl)-2-oxoethyl)-5-methoxy-2-methyl-1H-indole; 3-[2-(1H-Imidazol-1-yl)-2-oxoethyl]-5-methoxy-2-methyl-1-(4-chlorobenzoyl)-1H-indole; 1H-Indole-1-acetamide, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-(1H-imidazol-1-yl)-; Lornoxicam Impurity; Lornoxicam Related Compound; Oxicam Derivative; NSAID Intermediate
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Quality Control

Our 1-(4-Chlorobenzoyl)-3-(2-(1H-Imidazol-1-Yl)-2-Oxoethyl)-5-Methoxy-2-Methyl-1H-Indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Single Maximum Impurity ≤ 0.5%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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