Description

Praeruptorin E CAS NO 78478-28-1 is a high-purity, naturally occurring pyranocoumarin compound isolated from *Peucedanum praeruptorum* and related species. This compound is of significant interest for its role as a key reference standard and active pharmaceutical ingredient (API) intermediate in research and development. It is primarily sought by professionals in the pharmaceutical, biotechnology, and nutraceutical sectors for applications in pharmacological studies, quality control, and the synthesis of more complex molecules.

Application

• Pharmaceutical Research: Serves as a critical reference standard for the identification, assay, and purity testing of related coumarin derivatives in drug development pipelines.
• Bioactivity Studies: Used in in-vitro and in-vivo research to investigate potential pharmacological activities, including anti-inflammatory, cardiovascular, and neuroprotective effects.
• Natural Product Extraction & Standardization: Acts as a marker compound for the quality control and standardization of herbal extracts intended for use in dietary supplements and traditional medicine formulations.
• Chemical Synthesis: Employed as a building block or intermediate in the synthetic organic chemistry of novel drug candidates with enhanced bioactivity.
• Academic Research: Utilized in university and institutional labs for fundamental studies on the chemistry and biochemistry of pyranocoumarins.

Basic Information

Product Name	Praeruptorin E
CAS No.	78478-28-1
Molecular Formula	C₂₁H₂₂O₇
Molecular Weight	386.40 g/mol
Synonyms	Pd-Ib; (+)-Praeruptorin E; 3'(S),4'(S)-Diisovalerylkhellactone; cis-3',4'-Diisovalerylkhellactone; 3',4'-Di-O-isovalerylkhellactone; Khellactone 3',4'-diisovalerate; (3'S,4'S)-3',4'-Bis(3-methylbutanoyloxy)-3',4'-dihydroseselin
EINECS	Contact for details

Quality Control

Our Praeruptorin E is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and potency. A detailed Certificate of Analysis (COA) documenting purity, related substances, and residual solvents is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.