Description

(Tetrahydro-1H-Pyrrolizin-7A(5H)-Ylmethyl)Amine(Saltdata: 2Hcl) CAS NO 78449-73-7 is a specialized organic salt, primarily the dihydrochloride salt of a pyrrolizine-derived amine, valued for its role as a key synthetic intermediate in advanced pharmaceutical research. This compound is critical for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and novel therapeutic agents. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking high-purity building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of complex drug candidates, particularly those targeting neurological or inflammatory pathways.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the research and process development of new therapeutic compounds.
• Agrochemical Synthesis: Used in the research phase for creating novel pesticides or herbicides with specific biological activity.
• Biochemical Research: Employed as a standard or reagent in medicinal chemistry studies and structure-activity relationship (SAR) investigations.
• Fine Chemical Manufacturing: Integral to multi-step synthetic routes for producing high-value, low-volume specialty chemicals.
• Academic & Industrial R&D: A valuable compound for methodological development and exploratory synthesis in university and corporate laboratories.

Basic Information

Product Name	(Tetrahydro-1H-Pyrrolizin-7A(5H)-Ylmethyl)Amine Dihydrochloride
CAS No.	78449-73-7
Molecular Formula	C8H16N2 • 2HCl
Molecular Weight	221.14 g/mol (Free base: 140.23 g/mol)
Synonyms	7-(Aminomethyl)hexahydro-1H-pyrrolizine dihydrochloride; 1H-Pyrrolizin-7a(5H)-methanamine, hexahydro-, dihydrochloride; (Hexahydro-1H-pyrrolizin-7a-yl)methanamine dihydrochloride; Pyrrolizine-7a-methylamine dihydrochloride; 7a-(Aminomethyl)hexahydro-1H-pyrrolizine 2HCl; (Tetrahydro-1H-pyrrolizin-7a(5H)-ylmethyl)amine hydrochloride (2:1 salt); CAS 78449-73-7
EINECS	Contact for details

Quality Control

Our (Tetrahydro-1H-Pyrrolizin-7A(5H)-Ylmethyl)Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.