Description

1-Indolizinecarboxylic Acid, 2,3,5,6,7,8-Hexahydro-5-Thioxo-, Ethyl Ester is a specialized heterocyclic building block featuring a fused indolizine core with a thioxo and ester functional group. This compound is valued for its unique molecular architecture, making it a critical intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules and exploring novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing unique heterocyclic activity.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the indolizine scaffold can contribute to novel modes of action.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex, polycyclic frameworks due to its reactive thioxo and ester functionalities.
• Material Science Precursor: Investigated for the development of organic electronic materials or specialty polymers with specific optoelectronic properties.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes to study enzyme function or biological pathways.

Basic Information

Product Name	1-Indolizinecarboxylic Acid, 2,3,5,6,7,8-Hexahydro-5-Thioxo-, Ethyl Ester
CAS No.	78312-57-9
Molecular Formula	C11H15NO2S
Molecular Weight	225.31 g/mol
Synonyms	Ethyl 5-Thioxo-2,3,5,6,7,8-hexahydro-1-indolizinecarboxylate; 2,3,5,6,7,8-Hexahydro-5-thioxo-1-indolizinecarboxylic Acid Ethyl Ester; 1H-Indolizine-1-carboxylic acid, 2,3,5,6,7,8-hexahydro-5-thioxo-, ethyl ester; 5-Thioxo-2,3,5,6,7,8-hexahydroindolizine-1-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of 1-Indolizinecarboxylic Acid, 2,3,5,6,7,8-Hexahydro-5-Thioxo-, Ethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized using advanced analytical techniques including HPLC, GC-MS, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.