Description

Hydroxysafflor Yellow A is a high-purity, bioactive flavonoid compound isolated from *Carthamus tinctorius* L. (safflower). This compound serves as a critical reference standard and active ingredient, valued for its potent antioxidant and anti-inflammatory properties. It is essential for research and development in the pharmaceutical, nutraceutical, and cosmetic industries, where precise quality and reliable sourcing are paramount.

Application

• Pharmaceutical Reference Standard: Used for the identification, assay, and quality control of safflower-based drugs and herbal extracts in analytical laboratories.
• Active Pharmaceutical Ingredient (API): Incorporated into formulations targeting cardiovascular and cerebrovascular diseases due to its vasodilatory and neuroprotective effects.
• Nutraceutical & Dietary Supplements: Serves as a key bioactive marker in standardized safflower extracts for health supplements promoting blood circulation and antioxidant support.
• Cosmetic & Skincare Formulations: Utilized in anti-aging and skin-brightening products for its ability to inhibit tyrosinase and protect against oxidative stress.
• Biomedical Research: A vital tool in pharmacological and biochemical studies investigating mechanisms of action related to ischemia-reperfusion injury and inflammation.
• Traditional Medicine Standardization: Employed to authenticate and quantify the active components in safflower preparations used in Traditional Chinese Medicine (TCM).

Basic Information

Product Name	Hydroxysafflor Yellow A
CAS No.	78281-02-4
Molecular Formula	C27H32O16
Molecular Weight	612.53 g/mol
Synonyms	HSYA; Safflor Yellow A; Hydroxysafflor Yellow A; Carthamin Yellow A; 6-Hydroxykaempferol 3,6-di-O-glucoside; 6-Hydroxykaempferol 3,6-diglucoside; (2S,3R,4S,5S,6R)-2-[[(2R,3R,4S,5S,6R)-4,5-Dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R)-3,4,5-trihydroxyoxan-2-yl]oxyoxan-2-yl]oxymethyl]-6-(5,7-dihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)chromen-3-yl)oxyoxane-3,4,5-triol
EINECS	Contact for details

Quality Control

Our Hydroxysafflor Yellow A is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and identity confirmation by IR and MS. We provide Certificates of Analysis (COA) with detailed chromatographic data for traceability and compliance. The product meets high-purity standards suitable for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Loss on Drying	≤5.0%
Residue on Ignition	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.