Description

1H-Indole-2-Carboxylic Acid Benzyl Ester is a versatile and high-value synthetic intermediate, crucial for constructing complex molecular architectures. Its core value lies in its dual functionality, serving as a protected carboxylic acid derivative and a key indole-based building block for advanced research and development. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialized organic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, including potential kinase inhibitors and receptor modulators.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the indole scaffold imparts specific biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex heterocyclic compounds and natural product analogs.
• Material Science: Serves as a monomer or functional component in the research of advanced organic electronic materials and specialty polymers.
• Chemical Biology Probe Development: Utilized to create tagged or modified indole derivatives for studying biological pathways and protein interactions.

Basic Information

Product Name	1H-Indole-2-Carboxylic Acid Benzyl Ester
CAS No.	78277-27-7
Molecular Formula	C16H13NO2
Molecular Weight	251.28 g/mol
Synonyms	Indole-2-carboxylic acid benzyl ester; Benzyl 1H-indole-2-carboxylate; 2-Carbobenzyloxyindole; 1H-Indole-2-carboxylic acid, phenylmethyl ester; Benzyl indole-2-carboxylate; 2-Benzyloxycarbonylindole; NSC 405124; Bz-2-Ind-COOEt (common abbreviation)
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxylic Acid Benzyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, to verify identity and purity. A Certificate of Analysis (COA) detailing all relevant specifications is available for every batch upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.