Description

Ethyl 2-Anilino-4-Chloro-5-Formyl-3-Thiophenecarboxylate is a high-purity, multi-functional thiophene derivative serving as a critical advanced intermediate in organic synthesis. Its molecular architecture, featuring both formyl and ester functional groups, makes it a versatile building block for constructing complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Dye & Pigment Chemistry: Intermediate for synthesizing specialized thiophene-based dyes and colorants.
• Academic & Contract Research: Serves as a standard reagent for methodological studies in heterocyclic and medicinal chemistry.
• Custom Synthesis: Foundation for bespoke chemical manufacturing and scale-up projects requiring tailored molecular frameworks.

Basic Information

Product Name	Ethyl 2-Anilino-4-Chloro-5-Formyl-3-Thiophenecarboxylate
CAS No.	78267-24-0
Molecular Formula	C14H12ClNO3S
Molecular Weight	309.77 g/mol
Synonyms	Ethyl 5-Formyl-2-(phenylamino)-4-chlorothiophene-3-carboxylate; 2-Anilino-4-chloro-5-formyl-3-thiophenecarboxylic Acid Ethyl Ester; 4-Chloro-5-formyl-2-(phenylamino)thiophene-3-carboxylic Acid Ethyl Ester; 78267-24-0; Thiophene-3-carboxylic acid, 2-(phenylamino)-4-chloro-5-formyl-, ethyl ester; Ethyl α-(phenylamino)-4-chloro-5-formylthiophene-3-carboxylate
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2-Anilino-4-Chloro-5-Formyl-3-Thiophenecarboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be stored under an inert atmosphere to prevent oxidation and kept away from strong acids and bases.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.