Description

6,7-Dimethoxy-4-Phenyl 1,2,3,4-Tetrahydroisoquinoline Hydrochloride is a high-purity, advanced pharmaceutical intermediate belonging to the tetrahydroisoquinoline class of compounds. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting neurological and cardiovascular systems.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Alkaloid Synthesis: Serves as a fundamental building block for the preparation of complex isoquinoline and tetrahydroisoquinoline alkaloids and their analogs.
• Agrochemical Development: Employed in research for creating new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and enzyme functions.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental organic chemistry and pharmacological studies.

Basic Information

Product Name	6,7-Dimethoxy-4-Phenyl 1,2,3,4-Tetrahydroisoquinoline Hydrochloride
CAS No.	78238-94-5
Molecular Formula	C₁₇H₁₉NO₂·HCl
Molecular Weight	305.80 g/mol (Free base: 269.34 g/mol)
Synonyms	4-Phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 6,7-Dimethoxy-4-phenyl-1,2,3,4-tetrahydroisoquinoline HCl; 1,2,3,4-Tetrahydro-6,7-dimethoxy-4-phenylisoquinoline hydrochloride; NSC 339539; 4-Phenyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline monohydrochloride; 6,7-Dimethoxy-4-phenyl-3,4-dihydro-1H-isoquinoline hydrochloride
EINECS	Contact for details

Quality Control

Our 6,7-Dimethoxy-4-Phenyl 1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.