Description

3-(Methoxymethyl)-1H-1,2,4-Triazole-5-Thiol is a versatile heterocyclic building block featuring a reactive thiol group and a methoxymethyl substituent. This compound is valued for its role as a key intermediate in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research and development chemists and process engineers in fine chemical manufacturing for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of antifungal, antiviral, and other biologically active compounds containing the 1,2,4-triazole core.
• Agrochemical Synthesis: Used in the development of novel fungicides, herbicides, and plant growth regulators, leveraging its heterocyclic structure.
• Ligand and Chelating Agent: The thiol group allows it to act as a ligand in coordination chemistry or a building block for metal-organic frameworks (MOFs).
• Polymer Modification: Can be utilized to introduce functional groups into polymers or as a chain transfer agent in certain polymerization processes.
• Corrosion Inhibitor Precursor: Acts as a starting material for synthesizing specialized corrosion inhibitors used in industrial fluids.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	3-(Methoxymethyl)-1H-1,2,4-Triazole-5-Thiol
CAS No.	78201-12-4
Molecular Formula	C4H7N3OS
Molecular Weight	145.18 g/mol
Synonyms	5-Mercapto-3-(methoxymethyl)-1H-1,2,4-triazole; 3-(Methoxymethyl)-1,2,4-triazole-5-thiol; 1H-1,2,4-Triazole-5-thiol, 3-(methoxymethyl)-; 5-Thiol-3-methoxymethyl-1,2,4-triazole; Methoxymethyl-1,2,4-triazolethiol; 78201-12-4; 3-Methoxymethyl-1H-1,2,4-triazole-5-thiol
EINECS	Contact for details

Quality Control

Our 3-(Methoxymethyl)-1H-1,2,4-Triazole-5-Thiol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for synthetic applications. Each lot is analyzed using advanced techniques like HPLC, and a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.