Description

Fumoxicillin CAS NO 78186-33-1 is a semi-synthetic penicillin derivative, a key intermediate in the synthesis of advanced β-lactam antibiotics. Its primary value lies in its role as a crucial building block for producing high-potency, broad-spectrum antimicrobial agents. This compound is essential for pharmaceutical manufacturers and research institutions focused on developing and producing next-generation antibiotic formulations to address complex bacterial infections.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of advanced penicillin and amoxicillin-based antibiotic APIs.
• Antibiotic Research & Development: Serves as a key scaffold for medicinal chemists developing novel β-lactam compounds with improved efficacy and resistance profiles.
• Veterinary Medicine Production: Used in the formulation of antibiotic treatments for bacterial infections in livestock and companion animals.
• Fine Chemical Synthesis: Employed in specialized organic synthesis for creating complex molecules with the β-lactam core structure.

Basic Information

Product Name	Fumoxicillin
CAS No.	78186-33-1
Molecular Formula	C16H19N3O5S
Molecular Weight	365.41 g/mol
Synonyms	(2S,5R,6R)-6-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; Fumoxicillin; 4-Hydroxy-α-aminobenzylpenicillin; p-Hydroxyampicillin; BRL 2333 (ambiguous, verify context)
EINECS	Contact for details

Quality Control

Our Fumoxicillin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other pharmacopeial methods, to ensure it meets exacting standards for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting purity, related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and potency. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.