Description

L-Threo-Pentonic Acid, 2-Deoxy-, .Gamma.-Lactone is a specialized chiral lactone derivative, serving as a high-value intermediate in advanced organic synthesis. Its defined stereochemistry and functional group make it a critical building block for the development of complex molecules, particularly in pharmaceutical research. This compound is essential for chemists and manufacturers in the life sciences sector requiring precise, high-purity intermediates for API development and fine chemical production.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs), especially nucleoside analogs and antiviral compounds.
• Fine Chemical Synthesis: Used as a versatile building block for constructing complex natural products and other fine chemicals requiring specific stereochemical configurations.
• Biochemical Research: Employed in enzymatic studies and metabolic pathway research as a substrate or inhibitor due to its sugar acid lactone structure.
• Asymmetric Catalysis: Serves as a precursor or ligand in catalytic systems designed for stereoselective synthesis.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic routes in organic chemistry laboratories.

Basic Information

Product Name	L-Threo-Pentonic Acid, 2-Deoxy-, .Gamma.-Lactone
CAS No.	78185-09-8
Molecular Formula	C5H8O4
Molecular Weight	132.11 g/mol
Synonyms	2-Deoxy-L-threo-pentonic acid γ-lactone; (3R,4R)-3,4-Dihydroxy-5-methylidenedihydrofuran-2(3H)-one; L-Threo-2-deoxypentono-1,4-lactone; 2-Deoxy-L-threo-pentono-1,4-lactone; L-(-)-Three-2-deoxypentono-1,4-lactone
EINECS	Contact for details

Quality Control

Our L-Threo-Pentonic Acid, 2-Deoxy-, .Gamma.-Lactone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, enantiomeric purity, and impurity profiles. Our quality commitment aligns with the standards required for pharmaceutical intermediates and fine chemicals.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store in a cool, dry place at controlled room temperature (15-25°C). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain stability and prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.