Description

5-Nitroindazole-3-Carboxylic Acid is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its functionalized indazole core makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potent enzyme inhibitors, kinase inhibitors, and other novel therapeutic agents targeting various disease pathways.
• Agrochemical Research: Used as a building block for developing new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Chemical Synthesis: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science: Potential intermediate for creating advanced organic electronic materials and functional dyes due to its electron-withdrawing nitro group and carboxylic acid functionality.
• Bioconjugation & Probe Development: The carboxylic acid group allows for facile conjugation to biomolecules, making it useful for creating diagnostic probes and biochemical tools.

Basic Information

Product Name	5-Nitroindazole-3-Carboxylic Acid
CAS No.	78155-76-7
Molecular Formula	C8H5N3O4
Molecular Weight	207.14 g/mol
Synonyms	5-Nitro-1H-indazole-3-carboxylic acid; 3-Carboxy-5-nitroindazole; 5-Nitroindazole-3-carboxylic acid; 1H-Indazole-3-carboxylic acid, 5-nitro-; 5-Nitro-1H-indazole-3-carboxylic acid; 5-Nitroindazol-3-carbonsäure (German); Acide 5-nitro-1H-indazole-3-carboxylique (French)
EINECS	Contact for details

Quality Control

Our 5-Nitroindazole-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.