Description

Methyl 5-Fluoro-1H-Indazole-3-Carboxylate is a high-value fluorinated indazole derivative, a crucial synthetic intermediate in modern pharmaceutical chemistry. Its core value lies in providing a versatile, functionalized scaffold for constructing complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and development of new active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the indazole core.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, dyes, or functional polymers.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) exploring structure-activity relationships (SAR).
• Fluorinated Compound Library Synthesis: Used to create diverse chemical libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	Methyl 5-Fluoro-1H-Indazole-3-Carboxylate
CAS No.	78155-73-4
Molecular Formula	C9H7FN2O2
Molecular Weight	194.16 g/mol
Synonyms	5-Fluoro-1H-indazole-3-carboxylic acid methyl ester; Methyl 5-fluoroindazole-3-carboxylate; 3-Carbomethoxy-5-fluoroindazole; 5-Fluoro-3-methoxycarbonyl-1H-indazole; 1H-Indazole-3-carboxylic acid, 5-fluoro-, methyl ester; 5-Fluoro-1H-indazole-3-carboxylic acid, methyl ester; Methyl 5-fluoro-1H-indazol-3-ylcarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 5-Fluoro-1H-Indazole-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.