Description

(2-Aminobenzyl)Triphenylphosphonium Bromide is a versatile organophosphorus salt widely used as a key reagent in organic synthesis. Its primary value lies in its role as a stable ylide precursor for the Wittig reaction, enabling the efficient construction of carbon-carbon double bonds to form alkenes and heterocycles. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking reliable and scalable building blocks.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates, particularly those containing alkene or heterocyclic motifs.
• Wittig Olefination Reagent: Acts as a precursor to generate a stabilized ylide for the Wittig reaction, facilitating the synthesis of specific, often challenging, alkene products with control over stereochemistry.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides where specific alkene functionalities are required.
• Ligand and Catalyst Development: Employed in the preparation of novel phosphine-based ligands and organocatalysts for asymmetric synthesis and transition metal catalysis.
• Material Science Research: Utilized in the synthesis of organic semiconductors, liquid crystals, and polymers with tailored optical or electronic properties.
• Academic & Industrial R&D: A fundamental reagent for method development and exploratory chemistry in university laboratories and corporate R&D centers worldwide.

Basic Information

Product Name	(2-Aminobenzyl)Triphenylphosphonium Bromide
CAS No.	78133-84-3
Molecular Formula	C25H23BrNP
Molecular Weight	448.33 g/mol
Synonyms	(2-Aminophenyl)methyltriphenylphosphonium bromide; 2-(Triphenylphosphonio)benzylamine bromide; 1-(Triphenylphosphonio)-2-amino-benzene bromide; (2-Amino-benzyl)-triphenyl-phosphonium bromide; Triphenyl(2-aminobenzyl)phosphonium bromide; Phosphonium, (2-aminobenzyl)triphenyl-, bromide; (o-Aminobenzyl)triphenylphosphonium bromide
EINECS	Contact for details

Quality Control

Our (2-Aminobenzyl)Triphenylphosphonium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications, ensuring supply chain reliability for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.