Description

2-Acetyl-7-Chloro-1,2,3,4-Tetrahydroisoquinoline is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex pharmacologically active molecules, particularly within medicinal chemistry. Pharmaceutical R&D laboratories and fine chemical manufacturers need this high-purity intermediate to synthesize novel compounds targeting central nervous system disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those with tetrahydroisoquinoline scaffolds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new bioactive molecules for neurological targets.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex N-heterocycles through further functionalization.
• Agrochemical Research: Potential intermediate in the development of novel pesticides and herbicides due to its chlorinated heterocyclic structure.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and the discovery of new chemical entities.

Basic Information

Product Name	2-Acetyl-7-Chloro-1,2,3,4-Tetrahydroisoquinoline
CAS No.	78104-41-3
Molecular Formula	C11H12ClNO
Molecular Weight	209.67 g/mol
Synonyms	7-Chloro-2-acetyl-1,2,3,4-tetrahydroisoquinoline; 1-(7-Chloro-3,4-dihydro-1H-isoquinolin-2-yl)ethan-1-one; 2-Acetyl-7-chloro-1,2,3,4-tetrahydro-isoquinoline; 7-Chloro-2-acetyl-1,2,3,4-tetrahydroisoquinoline; 2-Acetyl-7-chlorotetrahydroisoquinoline; Ethanone, 1-(7-chloro-3,4-dihydro-1H-isoquinolin-2-yl)-; 7-Chloro-2-acetyl-3,4-dihydro-1H-isoquinoline
EINECS	Contact for details

Quality Control

Our 2-Acetyl-7-Chloro-1,2,3,4-Tetrahydroisoquinoline is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. All materials undergo rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.