Description

3-Thiophenecarboxylicacid,4-Fluoro-(9Ci) is a high-value fluorinated heterocyclic building block, specifically a derivative of thiophene-3-carboxylic acid. This compound is essential for introducing both the thiophene heterocycle and a fluorine atom into target molecules, enabling fine-tuning of electronic properties and metabolic stability. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of advanced intermediates, active ingredients, and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances bioactivity and environmental persistence.
• Material Science Research: Serves as a precursor for conjugated polymers and organic electronic materials, such as organic semiconductors and OLED components.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	3-Thiophenecarboxylicacid,4-Fluoro-(9Ci)
CAS No.	78071-32-6
Molecular Formula	C5H3FO2S
Molecular Weight	146.14 g/mol
Synonyms	4-Fluorothiophene-3-carboxylic acid; 4-Fluoro-3-thiophenecarboxylic acid; 4-Fluorothiophene-3-carboxylicacid; 3-Carboxy-4-fluorothiophene; 4-Fluoro-1,3-thiazole-5-carboxylic acid (tautomer); 78071-32-6; 4-Fluoro-thiophene-3-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Thiophenecarboxylicacid,4-Fluoro-(9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and synthesis. A Certificate of Analysis (COA) detailing purity (typically ≥97% by HPLC), identity confirmation, and impurity profile is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.