Description

3-Bromothiophene-2-Carboxamide is a high-purity brominated heterocyclic building block essential for advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel thiophene-based compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides that leverage the thiophene scaffold for bioactivity.
• Material Science Research: Serves as a precursor for functionalized thiophene monomers in the development of conductive polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent due to the reactive bromine handle for further functionalization via cross-coupling reactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, high-value brominated heterocycles.

Basic Information

Product Name	3-Bromothiophene-2-Carboxamide
CAS No.	78031-18-2
Molecular Formula	C5H4BrNOS
Molecular Weight	206.06 g/mol
Synonyms	2-Carbamoyl-3-bromothiophene; 3-Bromo-2-thiophenecarboxamide; 3-Bromothiophene-2-carboxylic acid amide; 3-Bromothiophene-2-carboxylic acid, amide; 3-Bromo-2-carbamoylthiophene; 3-Bromothiophene-2-carboxylic acid, amide; 3-Bromothiophene-2-carboxylic acid amide; 3-Bromothiophene-2-carboxamide
EINECS	Contact for details

Quality Control

Our 3-Bromothiophene-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.