Description

4-Bromo-2-(Trimethylsilyl)Thiophene is a high-value organosilicon building block and a key intermediate in advanced organic synthesis. This compound matters for its unique reactivity, where the bromine and trimethylsilyl groups serve as orthogonal handles for sequential functionalization, enabling the precise construction of complex heterocyclic systems. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional organic materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those containing complex thiophene or fused heterocyclic scaffolds for therapeutic applications.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the thiophene moiety contributes to biological activity.
• Organic Electronic Materials: Serves as a monomer or building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and solar cells.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis, facilitating challenging cross-coupling and other transformation reactions.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in synthetic methodology, enabling the exploration of new reaction pathways and molecular architectures.
• Functional Material Precursor: Used to create surface-modified materials and specialty chemicals with tailored properties for niche industrial applications.

Basic Information

Product Name	4-Bromo-2-(Trimethylsilyl)Thiophene
CAS No.	77998-61-9
Molecular Formula	C7H11BrSSi
Molecular Weight	235.22 g/mol
Synonyms	2-(Trimethylsilyl)-4-bromothiophene; 4-Bromo-2-trimethylsilylthiophene; Thiophene, 4-bromo-2-(trimethylsilyl)-; 4-Bromo-2-TMS-thiophene; 2-TMS-4-bromothiophene; 4-Bromo-2-(trimethylsilyl)thiophene; 4-Bromo-2-(trimethylsilyl)-thiophene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Trimethylsilyl)Thiophene is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.