Description

(1S,5R)-6,6-Dimethylbicyclo[3.1.1]Heptan-2-One is a high-purity, chiral bicyclic ketone that serves as a critical building block in advanced organic synthesis. Its defined stereochemistry and unique structural framework make it an invaluable intermediate for creating complex molecules with specific spatial orientations. This compound is essential for research and development in the pharmaceutical and fine chemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs), chiral catalysts, and specialty fragrances.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for stereoselective reactions.
• Fine Chemical Synthesis: Building block for creating complex natural product analogs and other high-value specialty chemicals.
• Fragrance & Flavor Chemistry: Intermediate in the production of sophisticated aroma chemicals with specific olfactory profiles.
• Agrochemical Research: Utilized in the development of new chiral pesticides and herbicides with enhanced efficacy.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialized polymers.

Basic Information

Product Name	(1S,5R)-6,6-Dimethylbicyclo[3.1.1]Heptan-2-One
CAS No.	77982-63-9
Molecular Formula	C9H14O
Molecular Weight	138.21 g/mol
Synonyms	(1S,5R)-(-)-Nopinone; (-)-Nopinone; (1S,5R)-6,6-Dimethyl-2-norpinanone; (1S,5R)-6,6-Dimethylbicyclo[3.1.1]heptan-2-one; L-(-)-Nopinone; (1S,5R)-(-)-6,6-Dimethylbicyclo[3.1.1]heptan-2-one; Nopinone, (-)-
EINECS	Contact for details

Quality Control

Our (1S,5R)-6,6-Dimethylbicyclo[3.1.1]Heptan-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its highly volatile and easily oxidized nature, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Specific Rotation [α]20/D	-25° to -30° (c=1 in CHCl3)
Refractive Index n20/D	1.470 - 1.475
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.