Description

6-Chloro-5-Nitro-2,3-Dihydro-1H-Indol-2-One CAS NO 77859-57-5 is a high-purity, synthetically versatile indole derivative. This compound serves as a critical advanced intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its nitro and chloro functional groups for structural diversification.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, including reduction, substitution, and cyclization reactions to create more complex heterocyclic systems.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and organic electronic materials due to its conjugated indole core.
• Biochemical Tool Compound: Utilized in academic and industrial research to study enzyme inhibition and biological pathways.

Basic Information

Product Name	6-Chloro-5-Nitro-2,3-Dihydro-1H-Indol-2-One
CAS No.	77859-57-5
Molecular Formula	C8H5ClN2O3
Molecular Weight	212.59 g/mol
Synonyms	6-Chloro-5-nitro-2-oxindole; 5-Nitro-6-chloro-2-oxindole; 6-Chloro-5-nitro-1,3-dihydro-2H-indol-2-one; 2H-Indol-2-one, 6-chloro-1,3-dihydro-5-nitro-; 6-Chloro-5-nitroindolin-2-one; 5-Nitro-6-chloroindolin-2-one; 77859-57-5; 6-Chloro-5-nitro-2,3-dihydroindol-2-one
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-Nitro-2,3-Dihydro-1H-Indol-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.