Description

2,3-Dihydroxypropyl Valproate is a valproic acid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a key intermediate or prodrug candidate, offering potential for improved drug delivery and metabolic profiles compared to the parent molecule. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel central nervous system (CNS) therapeutics, anticonvulsants, and mood stabilizers.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel valproate-based drug candidates and prodrugs.
• CNS Drug Research: Used in preclinical and research settings for developing new anticonvulsant, mood-stabilizing, and neuroprotective agents.
• Prodrug Development: Explored for its potential to enhance bioavailability, reduce side effects, or provide targeted release of valproic acid.
• Chemical Synthesis: Serves as a versatile synthon in organic chemistry for introducing the valproyl moiety into more complex molecular architectures.
• Reference Standard: Employed as an analytical standard in quality control and metabolic studies within pharmaceutical laboratories.

Basic Information

Product Name	2,3-Dihydroxypropyl Valproate
CAS No.	77656-37-2
Molecular Formula	C10H18O4
Molecular Weight	202.25 g/mol
Synonyms	Valproic Acid 2,3-Dihydroxypropyl Ester; 2,3-Dihydroxypropyl Valproate; 1,2-Dihydroxy-3-propyl Valproate; Propane-1,2,3-triol Valproate; Valproyl Glyceryl Ester; Glycerol Valproate Ester; 2,3-Dihydroxypropyl 2-propylpentanoate; 2-Propylpentanoic Acid 2,3-Dihydroxypropyl Ester
EINECS	Contact for details

Quality Control

Our 2,3-Dihydroxypropyl Valproate is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and development purposes. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material may be hygroscopic (moisture-sensitive); keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.