Description

2-Amino-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxamide is a high-value heterocyclic organic compound featuring a fused cyclopentane-thiophene core, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique bicyclic structure makes it an essential building block for the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators due to its bioactive thiophene scaffold.
• Material Science: Serves as a monomer or functional unit in the creation of organic semiconductors, conductive polymers, and advanced organic electronic materials.
• Chemical Synthesis: Acts as a versatile building block for constructing complex polycyclic frameworks in academic and industrial research laboratories.
• Dye & Pigment Industry: Utilized in the synthesis of specialized heterocyclic dyes and pigments with enhanced light-fastness and color properties.

Basic Information

Product Name	2-Amino-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxamide
CAS No.	77651-38-8
Molecular Formula	C8H10N2OS
Molecular Weight	182.24 g/mol
Synonyms	2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide; 2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide; 4,5,6,7-Tetrahydro-2-amino-benzo[b]thiophene-3-carboxylic acid amide; 2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid amide; 2-Amino-4,5,6,7-tetrahydrocyclohepta[b]thiophene-3-carboxamide (common misnomer); 2-Amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid amide; 77651-38-8; Aminocyclopentathiophenecarboxamide
EINECS	Contact for details

Quality Control

Our 2-Amino-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.