Description

γ-Butyrolactone-D6 is a deuterated isotopologue of γ-butyrolactone (GBL), where six hydrogen atoms are replaced by deuterium. This high-purity labeled compound is essential for applications requiring precise analytical tracking and minimal background interference. It is primarily used by researchers and quality control laboratories in the pharmaceutical, agrochemical, and analytical chemistry sectors for internal standards, metabolic studies, and NMR spectroscopy.

Application

• Internal Standard for Quantitative Analysis: Used in GC-MS and LC-MS methods for the accurate quantification of γ-butyrolactone and related compounds in complex matrices.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated solvent or a labeled reagent in nuclear magnetic resonance studies to elucidate molecular structures and reaction mechanisms.
• Metabolic Pathway Tracing: Employed in pharmaceutical and biochemical research to track the metabolic fate of GBL and its derivatives using mass spectrometry.
• Pharmaceutical Impurity Profiling: Acts as a reference standard in the identification and quantification of impurities and degradation products in active pharmaceutical ingredients (APIs).
• Chemical Synthesis Intermediate: Utilized as a labeled building block in the synthesis of deuterated complex molecules for research and development.
• Forensic and Toxicology Analysis: Applied as a certified reference material in forensic laboratories for the definitive analysis of controlled substances.

Basic Information

Product Name	γ-Butyrolactone-D6
CAS No.	77568-65-1
Molecular Formula	C₄D₆O₂
Molecular Weight	92.12 g/mol
Synonyms	GBL-D6; 1,4-Butanolide-D6; 4-Hydroxybutanoic acid lactone-D6; Tetrahydro-2-furanone-D6; 2-Oxotetrahydrofuran-D6; Butyrolactone-D6; 4-Butyrolactone-D6; γ-D6-Butyrolactone
EINECS	Contact for details

Quality Control

Our γ-Butyrolactone-D6 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, GC-MS, and HPLC, to ensure high isotopic purity and chemical purity. A detailed Certificate of Analysis (COA) specifying the isotopic enrichment (D-atom %), chemical assay, and impurity profile is provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Isotopic Purity (D-atom %)	≥ 98%
Chemical Purity (GC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.