Description

Ethyl (41R,13As)-13A-Ethyl-2,3,41,5,6,13A-Hexahydro-1H-Indolo[3,2,1-De]Pyrido[3,2,1-Ij][1,5]Naphthyridine-12-Carboxylate is a complex, high-purity heterocyclic organic compound with the CAS registry number 77549-94-1. This molecule serves as a critical advanced pharmaceutical intermediate or research chemical for the development of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers engaged in cutting-edge synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly in central nervous system (CNS) or oncology research.
• Organic Synthesis Research: Used in academic and industrial laboratories for methodological studies and the construction of novel polycyclic frameworks.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Process Chemistry Development: Used for scaling up and optimizing synthetic routes for potential commercial drug production.

Basic Information

Product Name	Ethyl (41R,13As)-13A-Ethyl-2,3,41,5,6,13A-Hexahydro-1H-Indolo[3,2,1-De]Pyrido[3,2,1-Ij][1,5]Naphthyridine-12-Carboxylate
CAS No.	77549-94-1
Molecular Formula	C23H28N2O2
Molecular Weight	364.48 g/mol
Synonyms	Ethyl 13a-ethyl-2,3,4a,5,6,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylate; (41R,13aS)-13a-Ethyl-2,3,4a,5,6,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid ethyl ester; UNII-9K5N6V6Y3I; 9K5N6V6Y3I; SCHEMBL23346877; ZINC000006043008; AKOS040759176; FT-0773299.
EINECS	Contact for details

Quality Control

Our Ethyl (41R,13As)-13A-Ethyl-2,3,41,5,6,13A-Hexahydro-1H-Indolo[3,2,1-De]Pyrido[3,2,1-Ij][1,5]Naphthyridine-12-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets exacting research and pharmaceutical-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.