Description

(15S)-19,20-Didehydro-17α-Methyl-21-Oxo-18-Oxayohimban-16β-Carbaldehyde is a complex, high-purity indole alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and reference standard for the development of novel therapeutic agents targeting the central nervous system. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of specialized alkaloid-based compounds. Our supply ensures the stringent purity and batch-to-batch consistency required for high-stakes discovery and process development work.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex indole alkaloid derivatives with potential pharmacological activity.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize new chemical entities, particularly for neurological targets.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) guidelines.
• Academic Research: Utilized in university and institutional labs for studying alkaloid chemistry, synthetic methodologies, and natural product synthesis.
• Biochemical Tool Compound: May be used to investigate specific biological pathways and receptor interactions in preclinical studies.

Basic Information

Product Name	(15S)-19,20-Didehydro-17α-Methyl-21-Oxo-18-Oxayohimban-16β-Carbaldehyde
CAS No.	77513-45-2
Molecular Formula	C₂₁H₂₂N₂O₃
Molecular Weight	350.41 g/mol
Synonyms	16β-Carboxy-19,20-didehydro-17α-methyl-21-oxo-18-oxayohimban; 18-Oxa-3,20-didehydroyohimban-16β-carbaldehyde, 17α-methyl-21-oxo-, (15S)-; 17α-Methyl-21-oxo-18-oxayohimban-16β-carbaldehyde; Yohimbine alkaloid derivative; Oxayohimban carbaldehyde derivative; (15S)-Form
EINECS	Contact for details

Quality Control

Every batch of (15S)-19,20-Didehydro-17α-Methyl-21-Oxo-18-Oxayohimban-16β-Carbaldehyde is produced and tested under a strict quality management system. We provide comprehensive analytical documentation, including a detailed Certificate of Analysis (COA) with results from HPLC, NMR, and mass spectrometry to confirm identity, purity, and strength. Our quality commitment ensures the material meets the exacting standards required for pharmaceutical R&D and is suitable for use as a reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.