Description

1-[3-(Trifluoromethyl)Phenyl]-1H-Pyrazol-4-Ol is a high-value fluorinated pyrazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring a trifluoromethylphenyl group, is engineered to impart desirable properties such as enhanced metabolic stability and lipophilicity to final compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to build novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty chemicals, including ligands for catalysis or monomers for advanced polymers.
• Chemical Biology & Proteomics: Employed as a scaffold or tagging agent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-[3-(Trifluoromethyl)Phenyl]-1H-Pyrazol-4-Ol
CAS No.	77458-38-9
Molecular Formula	C10H7F3N2O
Molecular Weight	228.17 g/mol
Synonyms	4-Hydroxy-1-[3-(trifluoromethyl)phenyl]-1H-pyrazole; 1H-Pyrazol-4-ol, 1-[3-(trifluoromethyl)phenyl]-; 3-(Trifluoromethyl)phenylpyrazol-4-ol; 4-Hydroxy-1-(3-trifluoromethylphenyl)pyrazole; 1-(3-Trifluoromethylphenyl)-1H-pyrazol-4-ol; 4-Pyrazolol, 1-[3-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 1-[3-(Trifluoromethyl)Phenyl]-1H-Pyrazol-4-Ol is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA), confirming identity, purity, and impurity profiles via techniques such as HPLC, NMR, and MS, is supplied with each shipment to guarantee reliable and consistent performance in your processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.