Description

Dyphylline Clofibrinate is a pharmaceutical-grade active pharmaceutical ingredient (API) that combines the bronchodilator properties of dyphylline with the lipid-modifying effects of clofibrate. This compound is valued for its dual therapeutic action, offering a targeted approach in specific pharmaceutical formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of advanced respiratory and metabolic therapies.

Application

• Pharmaceutical API: Primary use as an active ingredient in prescription medications targeting respiratory conditions.
• Combination Therapy Formulations: Development of fixed-dose combination drugs for complex cardiopulmonary disorders.
• Clinical Research: Serves as a key reference standard and investigational compound in pharmacological studies.
• Generic Drug Manufacturing: Production of generic versions of branded medications containing this API.
• Preclinical Development: Used in animal studies to evaluate efficacy, pharmacokinetics, and safety profiles.
• Analytical Testing: Employed as a high-purity standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Dyphylline Clofibrinate
CAS No.	77444-81-6
Molecular Formula	C20H25ClN4O5
Molecular Weight	436.89 g/mol
Synonyms	Dyphylline Clofibrate; 7-(2,3-Dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione 2-(4-Chlorophenoxy)-2-methylpropanoate; Clofibrate Dyphylline Salt; Dyphylline Clofibric Acid Ester; Theophylline Derivative Clofibrate; Dyphylline Ester of Clofibric Acid
EINECS	Contact for details

Quality Control

Our Dyphylline Clofibrinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets pharmaceutical-grade specifications, including identity, purity, and impurity profile verification. Certificates of Analysis (COA) documenting compliance with in-house specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.