Description

2,6-Dichloroaniline-3,4,5-D3 is a deuterium-labeled analog of 2,6-dichloroaniline, a key intermediate in chemical synthesis. This isotopically labeled compound is essential for creating internal standards used in advanced analytical techniques, ensuring precise and reliable quantitative measurements. It is primarily required by research institutions and pharmaceutical companies engaged in metabolism studies, environmental analysis, and the development of deuterated active pharmaceutical ingredients (APIs).

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference in LC-MS and GC-MS analysis for accurate measurement of 2,6-dichloroaniline and related compounds.
• Metabolite Tracing & Pharmacokinetics: Enables detailed tracking of drug metabolism and distribution in biological systems for pharmaceutical R&D.
• Environmental Fate Studies: Assists in monitoring the degradation and transformation of chloroaniline-based pesticides and herbicides.
• Synthesis of Deuterated APIs: Serves as a crucial building block for the preparation of deuterium-labeled drug candidates to enhance metabolic stability.
• Analytical Method Development & Validation: Critical for establishing robust, regulatory-compliant analytical methods in quality control laboratories.
• Isotope Dilution Analysis: Applied in high-precision quantification to correct for analyte loss during sample preparation.

Basic Information

Product Name	2,6-Dichloroaniline-3,4,5-D3
CAS No.	77435-48-4
Molecular Formula	C6H2D3Cl2N
Molecular Weight	164.04 g/mol (approx.)
Synonyms	2,6-Dichloroaniline-d3; 2,6-Dichloroaniline (phenyl-3,4,5-d3); 1-Amino-2,6-dichlorobenzene-3,4,5-d3; 2,6-Dichlorobenzenamine-d3; Deuterated 2,6-Dichloroaniline; 2,6-DCA-d3; (3,4,5-2H3)-2,6-Dichloroaniline; 2,6-Dichloroaniline (ring-D3)
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality protocols to ensure high isotopic purity and chemical integrity. Each batch is characterized by advanced spectroscopic and chromatographic methods, including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D-atom %), chemical purity, and identity confirmation is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.