Description

4-Chloro-n-(Cyclopropylmethyl)Benzo[D]Thiazol-2-Amine is a high-purity, advanced pharmaceutical intermediate with the CAS number 77414-62-1. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily needed by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of new fungicides and herbicides, leveraging the bioactivity of the benzothiazole core.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex molecular architectures for material science and chemical biology.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).

Basic Information

Product Name	4-Chloro-n-(Cyclopropylmethyl)Benzo[D]Thiazol-2-Amine
CAS No.	77414-62-1
Molecular Formula	C11H11ClN2S
Molecular Weight	238.74 g/mol
Synonyms	2-Amino-4-chloro-N-(cyclopropylmethyl)benzothiazole; 4-Chloro-2-[(cyclopropylmethyl)amino]benzothiazole; Benzo[d]thiazol-2-amine, 4-chloro-N-(cyclopropylmethyl)-; 77414-62-1; 4-Chloro-N-(cyclopropylmethyl)-1,3-benzothiazol-2-amine; 4-Chloro-2-(cyclopropylmethylamino)benzothiazole; 2-(Cyclopropylmethylamino)-4-chlorobenzothiazole
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-n-(Cyclopropylmethyl)Benzo[D]Thiazol-2-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical research and development applications. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.