Description

Ethyl 3-Amino-4-Methoxy-1-Benzothiophene-2-Carboxylate is a high-purity, functionalized benzothiophene derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex heterocyclic compounds, particularly in pharmaceutical research and development. This intermediate is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the benzothiophene core for biological activity.
• Material Science Research: Serves as a monomer or functional unit in the development of organic semiconductors, conductive polymers, and advanced organic electronic materials.
• Dye and Pigment Chemistry: Acts as an intermediate for synthesizing specialized heterocyclic dyes and organic pigments with specific light-absorption properties.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	Ethyl 3-Amino-4-Methoxy-1-Benzothiophene-2-Carboxylate
CAS No.	77373-52-5
Molecular Formula	C₁₂H₁₃NO₃S
Molecular Weight	251.30 g/mol
Synonyms	Ethyl 3-Amino-4-Methoxybenzo[b]thiophene-2-carboxylate; 3-Amino-4-methoxy-1-benzothiophene-2-carboxylic acid ethyl ester; 2-Carbethoxy-3-amino-4-methoxybenzothiophene; 2-Ethoxycarbonyl-3-amino-4-methoxybenzothiophene; 4-Methoxy-3-aminobenzothiophene-2-carboxylic acid ethyl ester; 77373-52-5; AMBC ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 3-Amino-4-Methoxy-1-Benzothiophene-2-Carboxylate is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.