Description

2-Acetamindo-2-(7-Chloroindol-3-Ylmethyl)Propanedioic Acid Dimethyl Ester is a specialized indole derivative with a complex molecular structure, serving as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex heterocyclic frameworks, particularly in the development of novel bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development for new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological or oncological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within R&D laboratories.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Academic Research: Employed in universities and research institutes for studying indole chemistry and developing new synthetic methodologies.
• Bioconjugation & Probe Synthesis: Potential use in creating chemical probes or tagged molecules for biological imaging and diagnostic applications.

Basic Information

Product Name	2-Acetamindo-2-(7-Chloroindol-3-Ylmethyl)Propanedioic Acid Dimethyl Ester
CAS No.	77306-52-6
Molecular Formula	C₁₇H₁₇ClN₂O₅
Molecular Weight	364.78 g/mol
Synonyms	Dimethyl 2-acetamido-2-[(7-chloro-1H-indol-3-yl)methyl]propanedioate; 2-Acetamido-2-[(7-chloro-1H-indol-3-yl)methyl]malonic Acid Dimethyl Ester; 2-Acetamido-2-(7-chloroindol-3-ylmethyl)malonic Acid Dimethyl Ester; Propanedioic acid, 2-acetamido-2-[(7-chloro-1H-indol-3-yl)methyl]-, 1,3-dimethyl ester; (7-Chloroindol-3-yl)malonate derivative; Acetamidomalonate indole derivative
EINECS	Contact for details

Quality Control

Our production of 2-Acetamindo-2-(7-Chloroindol-3-Ylmethyl)Propanedioic Acid Dimethyl Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development use. All materials are fully characterized and undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.